Name: DarkKinome
Owner: sorgerlab
Description: null
Created: 2017-03-05 20:28:00.0
Updated: 2017-03-05 20:41:37.0
Pushed: 2017-03-05 22:41:14.0
Homepage: null
Size: 36
Language: R
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The associated files are available on Synapse at: https://www.synapse.org/#!Synapse:syn8377973/files/
The scripts utilize the following R libraries: dplyr
, synapseClient
, reshape2
, ggplot2
The summary.tsv
table can be produced by running the following on the command line: Rscript wrangle.R
The Overall Score is computed according to the following criterion: s1 + 2*s2 + s3 + s4 + 5*s5
, where
s1 = 1/4 ( I(Recombinant Kinase) + I(3D Structure) + I(Antibody) + I(ThermoFisher) )
s2 = 1/2 ( I(Disease) + Normalized Genomic Aberration Score )
s3 = 1/2 ( I(Small Molecule Ligand) + Normalized Specificity Score )
s4 = Normalized Biological Activity Score
s5 = I( Expressed in LSP datasets )
To plot the results produced by the wrangling script, run the following on the command line: Rscript plot.R