cbcrg/robusta

Name: robusta

Owner: Notredame Lab

Description: A meta multiple genome alignment package

Created: 2014-07-30 12:31:09.0

Updated: 2014-07-31 20:29:39.0

Pushed: 2014-07-31 20:31:06.0

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Size: 192

Language: C

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README

Robusta

Robusta is a meta multiple genome alignment package.

It does not produce any alignment by itself but can combine alignments of different genome alignment programs into a single final alignment. It is able to call serveral different pairwise and multiple genome alignment programs. The results of these programs are parsed and turned into a T-Coffee library.

Using T-Coffee the alignments are then turned into the final alignment. Currently two pairwise genome aligner and three multiple genome alignment programs are included into this framework. A typical usage would be to cut the genomes to align into a set of collinear homologous blocks using Mercator.

These blocks are than aligned and turned into libraries using Robusta. As a final step T-Coffee is called to produce an alignment for each block.

Read more: http://www.tcoffee.org/Projects/robusta/


This work is supported by the National Institutes of Health's National Center for Advancing Translational Sciences, Grant Number U24TR002306. This work is solely the responsibility of the creators and does not necessarily represent the official views of the National Institutes of Health.