hackseq/2016_project_2

Name: 2016_project_2

Owner: hackseq

Description: Design a tool to optimize the parameters of any command line tool

Created: 2016-08-31 22:51:47.0

Updated: 2017-09-06 20:45:26.0

Pushed: 2017-09-06 20:45:25.0

Homepage: null

Size: 32664

Language: HTML

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README

Design a tool to optimize the parameters of any command line tool

Project Lead: Shaun Jackman / @sjackman / Graduate Student / BC Cancer Agency Genome Sciences Centre

Given a command line tool with a number of parameters and a target metric to be optimized, I want a tool that will run the program and find the values for those parameters that maximizes some target metric. My particular use case is genome sequence assembly, which often has a variety of parameters related to expected coverage of the reads and heuristics to remove read errors and collapse heterozygous variation. When I tackle that optimization, the process is manual and tedious: submitting jobs to a scheduler, rerunning failed jobs, inspecting outputs, tweaking parameters, and repeating. I want to design and implement a tool to automate that process and generate a report of the result.

Using parameter explorer app


This work is supported by the National Institutes of Health's National Center for Advancing Translational Sciences, Grant Number U24TR002306. This work is solely the responsibility of the creators and does not necessarily represent the official views of the National Institutes of Health.