Sage-Bionetworks/bfrmDemo

Name: bfrmDemo

Owner: Sage Bionetworks

Description: Demonstration code

Created: 2012-08-07 20:39:00.0

Updated: 2013-12-22 05:21:11.0

Pushed: 2012-08-08 15:37:01.0

Homepage: null

Size: 104

Language: null

GitHub Committers

UserMost Recent Commit# Commits

Other Committers

UserEmailMost Recent Commit# Commits

README

bfrmDemo

Code for demonstrating BFRM. The first QC script merely shows how an raw data from an experimentally-controlled perturbation of the Myc oncogene was normalized using a supervised method (gratis Brig Mecham of Sage Bionetworks). The second script shows the actual method where BFRM is used in two stages. First as a sparse ANOVA to identify genes with high posterior probability of being differentially expressed between the experiment and control data, and then using this feature list (restricted to posterior probability ? 0.99) to search for Myc-related factors. The 'projection' method is also quickly demonstrated here.


This work is supported by the National Institutes of Health's National Center for Advancing Translational Sciences, Grant Number U24TR002306. This work is solely the responsibility of the creators and does not necessarily represent the official views of the National Institutes of Health.