cBioPortal/oncoprintjs

Name: oncoprintjs

Owner: cBioPortal

Description: OncoPrint visualization

Created: 2014-12-15 18:25:58.0

Updated: 2017-12-17 15:45:18.0

Pushed: 2018-01-11 18:36:11.0

Homepage: null

Size: 1168

Language: JavaScript

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README

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OncoprintJS

This is the library that generates the Oncoprint visualization in cBioPortal. Essentially, it populates a canvas of a grid of m tracks of n types, where each element can either be a discrete value represented by a colored glyph on a grey background or a continuous value within a color range. Oncoprint can have many conceivable uses, but in cBioPortal, it is primarily used to visualize tracks of m genes and n patient samples, where the colored glyphs represent genomic alterations. It is also used to display a heatmap of gene and/or protein expression values for those m genes and n patient samples.

Using the Node Module

Oncoprint is on NPM. To install:

npm install --save oncoprintjs

In order to use it, just require it into your script.

const Oncoprint = require('oncoprintjs');

This will load the Oncoprint prototype into your environment. A full documentation of the API is still pending, but to see the basic usage in action, please follow the instructions below and take a look at the examples in the test/ directory.

Development
Getting Started

First, clone the repo:

git clone https://github.com/cBioPortal/oncoprintjs.git

Install the necessary NPM packages defined in package.json by running:

npm install

Next, execute

webpack

Which will write dist/oncoprint.bundle.js, which is a CommonJS module and can be included using require.

The directory rules/ contains glyph styling specifications that are specific to the genomic alterations use case of Oncoprint, which you may want to use.

Changes to Oncoprint

If you make changes to the Oncoprint code base and want to load it into the examples, do not modify oncoprint.bundle.js, since all of your code will get overwritten when compiled using webpack. Instead, modify the files in src/ and then re-run webpack.

Minimum Working Example

The test/ folder holds the code that runs the examples. All examples are mounted in index.html, which contains one JS file per example.

WARNING: THESE MAY NOT BE UP TO DATE AND MAY NOT WORK.

The file server.js starts the basic node server, serving files from dist/, rules/, and test/ on port 3000. To see the examples, execute the following:

node server.js

Note: These examples are very oversimplified versions of what is used in production versions of cBioPortal and are only meant to test code paths and give a sense of how the API connects together.


This work is supported by the National Institutes of Health's National Center for Advancing Translational Sciences, Grant Number U24TR002306. This work is solely the responsibility of the creators and does not necessarily represent the official views of the National Institutes of Health.