BilkentCompGen/mrfast

Name: mrfast

Owner: Bilkent Bioinformatics and Computational Genomics Group

Description: micro-read Fast Alignment Search Tool

Created: 2014-10-30 17:06:48.0

Updated: 2017-02-18 06:34:57.0

Pushed: 2016-01-29 20:01:46.0

Homepage: null

Size: 48

Language: C

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README

mrfast

micro-read Fast Alignment Search Tool

mrFAST is a read mapper that is designed to map short reads to reference genome with a special emphasis on the discovery of structural variation and segmental duplications. mrFAST maps short reads with respect to user defined error threshold, including indels up to 4+4 bp. This manual, describes how to choose the parameters and tune mrFAST with respect to the library settings. mrFAST is designed to find 'all' mappings for a given set of reads, however it can return one “best” map location if the relevant parameter is invoked.

NOTE: mrFAST is developed for Illumina, thus requires all reads to be at the same length. For paired-end reads, lengths of mates may be different from each other, but each “side” should have a uniform length.


This work is supported by the National Institutes of Health's National Center for Advancing Translational Sciences, Grant Number U24TR002306. This work is solely the responsibility of the creators and does not necessarily represent the official views of the National Institutes of Health.